Product Description:

Tris(2-carbonylethyl)phosphate hydrochloride(TCEP hydrochloride)is a new type of reducing agent and deprotecting agent for sulfhydryl DNA and also often used for the reduction of disulfide bonds in proteins,and can be used to prevent intramolecular or intramolecular protein formation between cysteines in proteins.Tris(2-carbonylethyl)phosphorus hydrochloride(TCEP hydrochloride)has higher stability,It is not easy to be oxidized by air,without any pungent odor,it is recognized as ideal reducing reagent.
 
Product Parameter:(产品参数)
 

CAS NO	51805-45-9	Density	1.041 g/mL at 25 °C
UN NO	3261 8/PG 2	Melting point	170.0-180.0℃
Molecular formula	C9H16ClO6P	Appearance and Smell	white crystal
Relative molecular weight	286.65	Colour	White

Product Advantages:

(1)No odor,can be used without fume hood;

(2)High stability,in the process of operation,use and storage do not need to do any preventive measures to avoid oxidation;

(3)Wide working range of pH;

(4)Strong reductivity,for most experiments,5-50 mM TCEP·HCl can provide sufficient molar force,at room temperature for a few minutes to fully reduce disulfide bonds;

(5)wide compatibility,does not contain mercaptan groups,downstream sulfhydryl modification experiments such as maleimide coupling does not need to remove the reducing agent in advance.

Product use:

Tris(2-carbonyl ethyl)phosphate hydrochloride is an organophosphorus compound,which can be used as a water-soluble reagent for selective reduction of disulfide.It is more stable than DTT in mass spectrometry application.It can also be used for selective reduction of disulfide in water.

Water soluble reagent for selective reduction of disulfide.It is more stable than DTT in mass spectrometric applications.For selective reduction of disulfide in water.After alkalization,the water-soluble ligand could be easily removed from the ruthenium complex decomposition catalyst by aqueous washing of the crude product.

Product storage：

Store at 2～8℃,away from light and humidity.